| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb8f3eba86915d967beefc175437273a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2009-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48b281b4beb4ca973814379145ebe308
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ba30d15b6014b14eca28ff85e78ae68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f82c8fea04bade829998e0bfe5a334a |
| publicationDate |
2011-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011053804-A1 |
| titleOfInvention |
Gene Signatures for the Prognosis of Cancer |
| abstract |
The cytokine TGFβ, in the tumor microenvironment, primes cancer cells for metastasis to the lungs. TGFβ response status (TBRS) can be determined by comparing expression levels of a panel of genes from cancer cells to the expression levels of the same genes in epithelial cell lines before and after induction with TGFβ. A TGFβ gene response signature reveals a clinical association between TGFβ activity in primary estrogen receptor negative (ER−) tumors and risk of lung metastasis. Further, combining the gene signature of the present invention with the known lung metastasis signature (LMS) increases the predictive value of the LMS considerably. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11640845-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020023676-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10016159-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11450409-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012100999-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2019093502-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11610644-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011182881-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013003384-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9458510-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019093502-A1 |
| priorityDate |
2008-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |