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filingDate 2010-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bd776c055cfab2fa63dca69f14a9aab
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publicationDate 2011-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2011046919-A1
titleOfInvention Method for accurate measurement of enzyme activities
abstract This invention relates to a novel method for the use of specialized equipment to significantly improve the accuracy with which enzyme activities are measured. The method establishes an internal standard mathematical curve for the measurement of relative values for each unit in a complex mixture. The novel feature of the method is that the control is an integral part of each and every sample, so that any variation in test conditions affects the control in exactly the same manner as the sample. Therefore, this novel method forces each measured sample to have a separate control internal to each sample that is exactly matched as to all possible variables. Although some prior methods claim an internal control, the prior methods provide only a rough calibration to an external control, which results in substantial deficiencies in accuracy, reliability, and efficiency.
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