| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_474b1e3e270c65debe808d291d6e3bd6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate |
2009-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3333e1b8176a8033617d70d02b18cd1d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c3d3b06d8dee253ed62fc29624da425
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06605278aa06b97b852e6f32b5eae51a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ec2d6607117b245844987ff704ad269 |
| publicationDate |
2011-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011034545-A1 |
| titleOfInvention |
Double-stranded lipid-modified rna having high rna interference effect |
| abstract |
An object of the present invention is to provide a novel double-stranded RNA that has high resistance to nuclease and cellular uptake efficiency and that can produce an excellent RNA interference effect. The present invention provides a double-stranded lipid-modified RNA comprising a sense strand having a nucleotide sequence complementary to a target sequence in a target gene, and an antisense strand having a nucleotide sequence complementary to the sense strand, the double-stranded RNA being capable of suppressing the expression of the target gene, and the sense strand having a double-stranded lipid bound directly or via a linker to at least one of the first to sixth nucleotides from the 5′ end. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11142769-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10238752-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11027023-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10934542-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10612020-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11597928-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9663784-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11786611-B2 |
| priorityDate |
2008-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |