| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3d952fdcdfd48e3cb69628ebbb737887
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6d426e40c59d97352c090dc3e3376af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4434bca6e8544d98122307bbc4f9568 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C381-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C279-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-197
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-54 |
| filingDate |
2010-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8116366e854d21bf499fc5e779dec91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a39f1491ca7ca57aa16f5ba97f69f9d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a8a6bd3e1fc9a025cd5bda24c9848f4 |
| publicationDate |
2011-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011028552-A1 |
| titleOfInvention |
Mexiletine amino acid and peptide prodrugs and uses thereof |
| abstract |
The present invention concerns prodrugs of mexiletine (and mexiletine's active metabolite) with amino acids or peptides and pharmaceutical compositions containing such prodrugs. Methods for providing pain relief, treating arrhythmia, decreasing the adverse GI side effects associated with mexiletine, increasing the bioavailability of mexiletine, and improving the pharmacokinetic reproducibility of mexiletine with the aforementioned prodrugs are also provided. Oligopeptides incorporating lysine or arginine residues attached directly or indirectly through a glycine residue are also described herein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022258842-A1 |
| priorityDate |
2009-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |