| abstract |
This invention provides a compound of the formula (I): n n n n n n n n n n a pharmaceutically acceptable salt or solvate thereof,n nwhereinn nR 1 is substituted or unsubstituted alkyl or the like,n nR 2 is hydrogen or substituted or unsubstituted alkyl,n nRing A is monocyclic or bicyclic aromatic heterocycle,n nR 3 is substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or substituted or unsubstituted heterocycle,n nR 4 is halogen, cyano, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl or the like,n nm is an integer between 0 and 2,n nn is an integer between 0 and 5,n nR is halogen, oxo, cyano, nitro, substituted or unsubstituted alkyl or the like, andn np is an integer between 0 and 2n nas novel compounds having NPY Y5 antagonistic activity. |