http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011027871-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a92ee92f574c437a3cf4130dbfe62889 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3683 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-32 |
| filingDate | 2010-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8aa3cd31bc14af93e4ffcddaf0ced85c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6d8b26b0b5e2a4af6dd7504d6bc385f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fb2061bae57c4124681a46e09f48ec7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_411dc6aaebd444ad2e27953297c86ec9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb377c59a835d8310523e7d5b5d9eb05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9aa88eb2de7e222db821186183e96ad4 |
| publicationDate | 2011-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2011027871-A1 |
| titleOfInvention | Apparatus for Demineralizing Osteoinductive Bone |
| abstract | The invention is directed to an apparatus for producing demineralized osteoinductive bone. The apparatus demineralizes bone by subjecting bone, including, for example, ground bone, bone cubes, chips, strips, or essentially intact bone, to either a rapid high volume pulsatile acidification wave process or to a rapid continuous acid demineralization process. The pulsatile acidification wave process includes subjecting bone to two or more rapid pulse/drain cycles in which one or more demineralizing acids is rapidly pulsed into a vessel containing bone, and after a desired period of time, is rapidly drained from the vessel. The continuous acid demineralization process includes subjecting bone to a continuous exchange of demineralizing acid solution in which the demineralizing acid solution is recirculated from the container holding the bone through an ion exchange media. Calcium and phosphate are thereby removed from the bone to produce a regenerated acid, and the regenerated acid is returned to the container holding the bone. Both processes allow bone to be rapidly demineralized to a precise and specific desired residual calcium level without sacrificing osteoinductivity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11596517-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10531957-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018190614-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10130736-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11305035-B2 |
| priorityDate | 1999-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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