Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_64fab711e94aa910dfb7511bb1bf834e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-04 |
filingDate |
2009-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_128cd4d122a6e96c4e5a04965d8f27e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_411343f549ce574170d98c9b9d0ad210 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b893764d0542c7e29fcf2fa023f2c34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fde2a138aa7d3fd8b12bcf4d8552a03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1e155d192dac1cad21e92098762dbf7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ae89276e7376ed9e3bec7bf1b8b6c6e |
publicationDate |
2011-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011021793-A1 |
titleOfInvention |
Process for preparing nebivolol |
abstract |
The present invention relates to a process for reducing a compound of formula (I) wherein X is halogen, a hydroxy group, an alkylsulfoniloxy group or an arylsulfonyloxy group; to give a compound of formula (II) as a di-astereoisomerically pure compound of RS/SR configuration characterized in that said reduction is carried out by the use of (+)-B-chlorodiisopinocampheylborane or (−)-B-chlorodiisopinocampheylborane. The compounds of formula (II) are useful as intermediates for the preparation of Nebivolol. |
priorityDate |
2008-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |