| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7363b18563596a1c46561f66517ba84c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-00051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-00023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-18022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5258
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5256
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-10061
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-18052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-10051 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
2006-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d011682377a6f5d0bcf43539f2c6d81c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7eae23a8c3ad13f1909a5aa8eb2eacb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd8a6cc02ffa6ded55ff4346715b0b0e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51561ea7713ee4fb8730dfa0f5e961e6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5a2a6b0ee97ed8373ae8477f63c7e76 |
| publicationDate |
2011-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2011008831-A1 |
| titleOfInvention |
Scalable fermentation process |
| abstract |
This invention provides a robust fermentation process for the expression of a capsid protein of a bacteriophage which is forming a VLP by self-assembly, wherein the process is scalable to a commercial production scale and wherein the expression rate of the capsid protein is controlled to obtain improved yield of soluble capsid protein. This is achieved by combining the advantages of fed-batch culture and of lactose induced expression systems with specific process parameters providing improved repression of the promoter during the growth phase and high plasmid retention throughout the process. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11142745-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2016242996-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11285210-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10604736-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016161305-A1 |
| priorityDate |
2005-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |