Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fb3896d82f60e3d775635fa3b6ff079 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-60 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0053 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
filingDate |
2008-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e3b6470a49ae4e915094c0506125523 |
publicationDate |
2011-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2011008778-A1 |
titleOfInvention |
Method of Generating p° Cells |
abstract |
Described is a method of the generation of ρ° cells using a mitochondrial targeted restriction endonuclease. This method comprises (a) tranfecting cells with an expression vector containing a gene encoding a fusion protein comprising a mitochondrial targeting sequence (MTS) and a restriction endonuclease operatively linked to a suitable promoter, (b) culturing the transfected cells over a sufficient period of time; and (c) selected ρ° cells, e.g., via FACS analysis. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018034728-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020036973-A1 |
priorityDate |
2007-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |