Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e29526f284c0155fd79806c9dd5a1c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d595ec481a2a081fed4aa2fd4ff52d8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate |
2008-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97f94049e43c7e07de416ebe0b3d8f1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55db2ef54403aceef904862fe0b71cab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc9ac6e3eaa809514f66c6fe9b1d4782 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ce7f6fea0efd8e2893b9ee146922bfb |
publicationDate |
2010-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010284999-A1 |
titleOfInvention |
Characterization of the cbir1 antigenic response for diagnosis and treatment of crohn's disease |
abstract |
This invention provides methods of diagnosing or predicting susceptibility to Crohn's Disease by determining the presence or absence of genetic variants. In one embodiment, the present invention provides methods to diagnose and/or predict susceptibility to Crohn's Disease in an individual by determining the presence or absence of anti-Cbir1 reactivity and the presence or absence of TLR5 risk variants. In another embodiment, the present invention provides methods to diagnose Crohn's Disease by determining the presence or absence of NFKB1 haplotype H3 and/or ASCA expression. In another embodiment, the present invention provides methods of diagnosing Crohn's Disease by determining the presence or absence of Cbir1 specific peripheral blood T cell proliferation. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9580752-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8486640-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11312768-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11268149-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2689246-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012135142-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11236393-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11186872-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103175971-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10544459-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10633449-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2689246-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10316083-B2 |
priorityDate |
2007-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |