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publicationDate 2010-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2010284912-A1
titleOfInvention Homogenization of a radiopharmaceutical using sonification and/or rotor-stator technology to produce a homogenous suspension, emulsion, mixture or solid suspension of immiscible ingredients
abstract A homogenous dispersion of aqueous droplets of a radiopharmaceutical or radiodiagnostic agent within a non-aqueous medium and method of making the same is provided. The homogenous dispersion is largely free of impurities and constitutes a substantially uniform distribution of sodium thiosulfate and radiopharmaceutical which is stable for a time sufficient to fill and solidify within gel capsules. In making the homogenous dispersion, dry sodium thiosulfate and dry potassium phosphate dibasic anhydrous are uniformly dispersed within non-aqueous, liquid polyethylene glycol.
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