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publicationDate 2010-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2010279876-A1
titleOfInvention Detection of nucleic acid sequence differences by comparative genomic hybridization
abstract The present invention provides a method of detecting nucleotide sequence differences between two nucleic acid samples. The method employs a comparative genomic hybridization (CGH) technique to analyze the sequence differences between the samples. This method permits the identification of small sequence differences (e.g., sequence divergence of 1% or less) in nucleic acid samples of high complexity (e.g., an entire genome).
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