http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010256160-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4eb6dbca25e5f9459a6c5f592728c787 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2007-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6192499edc83eb8605ff0e8722ce4cb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2850637ea47707fc03362e05ce27377c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_743cfad2801d78fe79cb045f15f77074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d690b9703acfb39a0598b8667a93dbc |
| publicationDate | 2010-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2010256160-A1 |
| titleOfInvention | Method of administering an antitumor compound |
| abstract | The present invention provides a method of treating a mammal, including humans, suffering from tumour, comprising administering Compound 1 of the formula A or a pharmaceutically acceptable salt thereof, to said mammal by intravenous infusion, characterised in that Compound 1 is conveniently administered employing particular schedules, infusion times and doses which allow a more efficacious treatment. Compound 1 of formula A is an aurora inhibitor, chemical name N-{5-[(2R)-2-methoxy-2-phenylethanoyl]-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl}-4-(4-methylpiperazin-1-yl)benzamide, and the method is preferably for the treatment of patients having solid tumours or hematopoietic malignant tumours. The use of Compound 1, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier or excipient, in the manufacture of a medicament for the treatment of tumours employing particular schedules, infusion times and doses, as well as the use of Compound 1 for treatment of tumours in the same manner are also provided. |
| priorityDate | 2006-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.