| abstract |
A compound having the following formula (II) or its pharmacologically acceptable salt is used as a P2X 4 receptor antagonist: n n n n n n n n n n in whichn R 11 represents hydrogen or an alkyl group having 1-8 carbon atoms; R 21 represents an alkyl group having 1-8 carbon atoms, an alkoxy group having 1-8 carbon atoms, an alkyl group having 1-8 carbon atoms and having 1-3 halogen substituents, or hydroxyl; and R 31 is hydrogen or a halogen atom. |