Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2dc9a78dd4b3a699238d6c136eab8d02 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55561 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 |
filingDate |
2010-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aeeaecb9a85afbcb54c2e4fadf43b228 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_073f9d808d98b02d8e5c762c89db3b1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5f01a042edea66084ef4ef9113917e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de69d05f1bd46e003a37caf8d0533e7c |
publicationDate |
2010-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010254974-A1 |
titleOfInvention |
Modulation of Immunostimulatory Properties of Oligonucleotide-Based Compounds by Optimal Presentation of 5' Ends |
abstract |
The invention relates to the therapeutic use of oligonucleotides as immunostimulatory agents in immunotherapy applications. More particularly, the invention provides immunomers for use in methods for generating an immune response or for treating a patient in need of immunostimulation. The immunomers of the invention comprise at least two oligonucleotides linked at their 3′ ends, internucleoside linkages or functionalized nucleobase or sugar to a non-nucleotidic linker, at least one of the oligonucleotides being an immunostimulatory oligonucleotide and having an accessible 5′ end. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103501794-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014051637-A1 |
priorityDate |
2001-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |