| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40b922ff081632b6c633ff8dc46fb7c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0113b37caab3e120aace5a21cd971a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6436bcba24723aaacc2c0c1aa46dfef1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_89a8aa9db8074e7174d76f88e9106f25 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24027 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-96 |
| filingDate |
2009-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c45c55baa6f9bbece97096b81a4a517f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bb2f15f20ced2356d16f89248929c85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e35c69c22029605230d4901e48eae848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b91551ce3cd37c70594158fbce133a3 |
| publicationDate |
2010-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010248326-A1 |
| titleOfInvention |
Stabilization of thermolysin in aqueous solution |
| abstract |
The present invention deals with the proteolytic enzyme thermolysin which tends to be unstable in aqueous solution. The invention provides methods and compositions to enhance the stability of dissolved thermolysin in aqueous solution. Thermolysin, crude thermolysin or a lyophilisate containing thermolysin and one or more salts, is contacted with an aqueous buffer with a low salt concentration and a first solution is formed. Subsequently, a further salt in solid form is added and dissociated, thereby forming a second solution comprising thermolysin in a stabilized form. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11359190-B2 |
| priorityDate |
2008-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |