| abstract |
A biosensor which comprises a substrate ( 101 ) having a buried electronic sensing element and a substrate surface ( 124 ) above the buried electronic sensing element; a structured top layer ( 125 ) covering the substrate surface ( 124 ), having a top surface above the substrate surface ( 124 ), and comprising at least one stimulation and/or sensing electrode ( 116 ) and a channel ( 121 ) for holding the biomolecule by means of suction through said channel ( 121 ) arranged between the top surface ( 125 ) and the substrate surface ( 124 ), the sensing electrode ( 116 ) being electrically coupled to the electronic sensing element; wherein the top surface ( 125 ) is provided for placing a biomolecule present in a sample solution thereupon, the sensing electrode ( 116 ) is provided for sensing electrical variations in and presence of the biomolecule. |