| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bc5292a07e34d16eb1d033a16d3aec3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_676b80da7ac92b84e447a83fb1630ae1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57423
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2008-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccac8109d8d6dc43dd6c05b9183f77cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f21093ce98f1085016201757abe91a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91fc7b8cf3b38ee47b21a7018099a157 |
| publicationDate |
2010-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010233695-A1 |
| titleOfInvention |
Molecular diagnosis and typing of lung cancer variants |
| abstract |
Compositions and methods useful in determining the major morphological types of lung cancer are provided. The methods include detecting expression of at least one gene or biomarker in a sample. The expression of the gene or biomarker is indicative of the lung tumor subtype. The compositions include subsets of genes that are monitored for gene expression. The gene expression is capable of distinguishing between normal lung parenchyma and the major morphological types of lung cancer. The gene expression and somatic mutation data are useful in developing a complete classification of lung cancer that is prognostic and predictive for therapeutic response. The methods are suited for analysis of paraffin-embedded tissues. Methods of the invention include means for monitoring gene or biomarker expression including PCR and antibody-based detection. The biomarkers of the invention are genes and/or proteins that are selectively expressed at a high or low level in certain tumor subtypes. Biomarker expression can be assessed at the protein or nucleic acid level. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012239309-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9043249-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107849613-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107208131-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015184461-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113373212-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11041214-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10934595-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016201143-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014148353-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10829819-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011207618-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110412277-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016168446-A1 |
| priorityDate |
2007-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |