| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f490a4a144924de1f395163f7f65d58a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2310-00365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3895
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-386
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3662 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate |
2008-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa35475f8aae4310b1483a12cbd0540b |
| publicationDate |
2010-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010233233-A1 |
| titleOfInvention |
Tenocyte containing bioscaffolds and treatment using the same |
| abstract |
The present invention relates to methods for preparing bio scaffolds useful in the repair of tears. More specifically, the invention relates to a method of treating rotator cuff tear in a mammalian subject in need thereof comprising the steps of: (i) selectively expanding tenocytes in vitro in culture medium comprising insulin or a functional derivative and a glucocorticoid or a glucocorticoid-like molecule to produce a culture of expanded tenocytes; (ii) seeding a bioscaffold with said expanded tenocytes to produce a tenocyte seeded bioscaffold; and (iii) implanting said tenocyte seeded bioscaffold proximal to the rotator cuff tear. The present invention also relates to a bioscaffold comprising cells, wherein more than 80% of said cells are tenocytes. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9434923-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11020509-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014193377-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8986678-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11338056-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11338057-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113874192-A |
| priorityDate |
2007-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |