Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60dae4ecb78c9f499de06dec2cdcfb00 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 |
filingDate |
2007-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6daa3e54d22a3e3707c97258858ac272 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6525ddb1c9f0aa729cda7b45da93bc6a |
publicationDate |
2010-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010221759-A1 |
titleOfInvention |
Assay for the diagnosis of alzheimer's disease based on the determination of the ratio of gamma-secretase abeta cleavage products |
abstract |
Described is a method for the diagnosis of Alzheimer's disease (AD) or a particular stage of the disease which is based on the determination of the ratio of at least two gamma-secretase cleavage products, Abeta48, Abeta45, Abeta42, Abeta38 and Abeta35, preferably the ratio of Abeta38: Abeta42. A decreased ratio of Abeta38: Abeta42 as compared to the normal ratio is indicative of AD. Moreover, kits suitable for carrying out said diagnostic method are described. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010028918-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005142622-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009239311-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9678086-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014128329-A1 |
priorityDate |
2006-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |