| abstract |
The present invention provides a compound represented by the formula: n n n n n n n n n n wherein n R 1a is a hydrogen atom, n R 2a is a C 1-6 alkyl group substituted by a group represented by —NR 6a —CO—(CH 2 ) n —SO 2 — optionally halogenated C 1-4 alkyl n wherein n is an integer of 1 to 4, R 6a is a hydrogen atom or a C 1-4 alkyl group, and —(CH 2 ) n — is optionally substituted by C 1-4 alkyl, n R 3a is a hydrogen atom or a C 1-6 alkyl group, n R 4a is a halogen atom or a C 1-6 alkyl group, n R 5a is a halogen atom or a C 1-6 alkyl group, and n X a is a hydrogen atom or a halogen atom, n or a salt thereof. n n n The compound of the present invention has a superior tyrosine kinase inhibitory action, is highly safe, and is sufficiently satisfactory as a pharmaceutical product. |