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filingDate 2009-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2010-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2010198774-A1
titleOfInvention Systems and Methods for Aligning Multiple Point Sets
abstract Many biological data analysis problems require matching data points from different data sets. For example, high-throughput protein expression liquid chromatography and mass spectrometry (LC/MS) protocols developed generate 2-dimensional feature sets that require matching on a point-by-point basis. In these protocols, it can be useful to perform all data collection sequentially and analyze the data subsequent to lab work. This avoids the need to identify all of the components in a sample before comparing it to other samples, thus saving effort and avoiding the potential problem of missing an important component due to problems in the identification stage. Such methods can involve identifying, grouping and measuring sets of characteristic peaks in order to identify and quantify shared peptides. The present teachings provide, among other things, a method for comparing and associating multiple data sets. These methods, can be used, for example, for analyzing LC/MS runs, gel images etc.
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