Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f01715f8b6f3045e49c07d5823279db9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fe9e7461213a24ccc1039ba6991854d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_290c086fac006f0826d152edc6f93df7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-18 |
filingDate |
2010-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3f2b39caf9fe2c90b82175d5fcfef60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14afcf3f7be17c26df14716a6970e2a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5dcfb9411988827d64009df4ac5eda3 |
publicationDate |
2010-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010184846-A1 |
titleOfInvention |
Methods for the formulation and manufacture of artesunic acid for injection |
abstract |
A method for the manufacture of a sterile intravenous or intramuscular formulation of artesunic acid and the formulation are the subject of this invention. First the artesunic acid powder is sterilized with ethylene oxide and placed into a sterile container. The contained sterilized powder is then dissolved in sterile sodium phosphate buffered solution to produce an injectable intravenous or intramuscular formulation. The sodium phosphate dissolves and dilutes the artesunic acid powder without caking or frothing resulting in an improved drug product. The invention also relates to the formulation and a method of treating a patient with either uncomplicated or severe and complicated malaria. |
priorityDate |
2006-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |