Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f57eb2aae1c6dd49596233afe26cf95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b62009d3940a6cd8bfbab97ba2ef28c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 |
filingDate |
2009-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0154d39747210e8ca0c5a5127f2422b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_065aa77c5410546776ce6ea14c566ab3 |
publicationDate |
2010-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010184837-A1 |
titleOfInvention |
Small-molecule nucleotide aptamer for hepatitis C virus, preparation method and use thereof |
abstract |
A DNA aptamer specific for HCV having a nucleotide sequence as shown in SEQIDNO.1-29, and a method of preparing the same including the steps of: (1) constructing a single-stranded DNA library; (2) constructing a double-stranded DNA library; (3) screening by SELEX; (4) amplifying by PCR; (5) cloning and sequencing; and (6) testing the effect from cellular level in vitro. The DNA aptamer can be used directly as medication and diagnostic reagent for detection, prevention, and treatment of hepatitis C. A method for detection of HCV infection is also provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101480495-B1 |
priorityDate |
2008-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |