| abstract |
The various embodiments of the present invention are generally directed to systems and methods to affect anatomical structures. More particularly, the various embodiments of the present invention are directed to systems and methods to regenerate bone. An aspect of the present invention comprises a system for affecting an anatomical structure, comprising: a nanofiber mesh configured to substantially conform to an anatomical structure, wherein at least a portion of the nanofiber mesh defines a fillable space; a carrier substance comprising an active agent, such as a bone morphogenetic protein, wherein the carrier substance is disposed within the fillable space. |