Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e3113097dd6d28720572e47f2f2407 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
filingDate |
2008-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6114b9f75a06011498ae5c6ea5eb2b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2faaa26a616b64de7c1c88114ee027b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39a0738b6b7ed0557e753660b70d8556 |
publicationDate |
2010-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010166853-A1 |
titleOfInvention |
Coated preparation |
abstract |
The present invention provides a preparation containing pioglitazone or a salt thereof as an active ingredient, which shows high bioavailability of pioglitazone and less interindividual variation in blood drug concentration, as well as a preparation with suppressed color change during preservation. The preparation contains a core containing a pharmaceutically acceptable organic acid with water solubility at 20° C. of not less than 10 mg/mL and pK a1 (a negative common logarithm of the first acid dissociation constant K a1 ) at 25° C. of not more than 5, and a coating layer containing pioglitazone or a salt thereof. The coating layer may further contain mannitol or trehalose. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012241402-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016199307-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9907789-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012096873-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014248362-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9339543-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2765855-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9238571-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2765855-A4 |
priorityDate |
2007-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |