http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010160652-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62a3119a692179555302c0a34599f4c8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
| filingDate | 2009-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd24933cd7719fb7f0c2af5a789bfbb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9e6602bf1cf791db3056b7b7d753260 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4901afdb1617ef4dda0988f2f2ae04ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_797f39e347770af0402a583f1d3b7ab5 |
| publicationDate | 2010-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2010160652-A1 |
| titleOfInvention | Stereospecific method for the preparation of dioxa-bicyclooctane nitrate compounds |
| abstract | This invention relates to a new method for the stereospecific thiocarboxylation and nitration of organic compounds for the preparation of compounds according to formula (I): n n n n n n n n n n n n comprising the following steps: n (a) reacting a compound of formula (II): n n n n n n n n n n n n n n n n with a sulfonic derivative of formula (III) n n n n n n n n n n n n n n n n wherein the R is chosen from the groups C 1-3 -alkyl, C 1-3 -alkyl substituted with 1 to 3 halogen atoms, phenyl, C 1-3 -alkyl-phenyl and C 1-3 -alkyl-phenyl wherein the alkyl is substituted with 1 to 3 halogen atoms and G is a halogen atomo or a group —O—SO 2 —R wherein R is as hereinabove defined n to yield a compound of formula (IV) n n n n n n n n n n n n n n n n (b) treating compound (IV) with a thiocarboxylic acid of formula (V) or a salt thereof: n n n n n n n n n n n n n n n n wherein Z is as defined above, to yield compound (VI) n n n n n n n n n n n n n n n n and n (c) treating compound (VI) with tetrabutylammonium nitrate to yield a compound of formula (I). |
| priorityDate | 2008-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 304.