Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fcb093a174d5182b5854b704cb09354 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-16 |
filingDate |
2010-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c1e8d1a38c2a56567388c85bffdd187 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75e6da4928e62b4dd647fa306336b021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6ccdcc23557e1c5d04629451145f8c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaddd93fc68d881bbf9812a30f7655f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aa6698283ee678ae9a18b7a7b788dee |
publicationDate |
2010-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010152237-A1 |
titleOfInvention |
Bis-pyrindino containing compounds for the use in the treatment of cns pathologies |
abstract |
N-n-Alkylation of nicotine converts nicotine from an agonist into an antagonist specifically for neuronal nicotinic acetylcholine receptor subtypes mediating nicotine-evoked dopamine release. Conformationally restricted analogs exhibit both high affinity and selectivity at this site, and are able to access the brain due to their ability to act as substrates for the blood-brain barrier choline transporter. |
priorityDate |
2003-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |