http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010152140-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_baffa86c0e70f61112d4ac6ab59b3e4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae4bdd20c4b5ee4bb2f806cd50e59c48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c1178cec6e91b3a753e5392e7eae9c4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-66 |
| filingDate | 2008-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be066aba90e46236d8f6239b0d76092e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5113112973904593dba8c06a1a2cd7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cabaf07839b6cd223cd5245c8e69732 |
| publicationDate | 2010-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2010152140-A1 |
| titleOfInvention | Method of Cancer Treatment with Naphthol Analogs |
| abstract | In one embodiment, the present invention relates to a method of treating a cancer characterized by overexpression of cyclic adenosine monophosphate response element-binding protein (CREB) or phosphorylated CREB (p-CREB) by administering to a patient suffering from the cancer a pharmaceutically-effective amount of a composition comprising a compound selected from the group consisting of 2-{1-[3-(Amidinothio)propyl]-1H-indol-3-yl}-3-(1-methylindol-3-yl)maleimide, naphthol analogs having the structure (I), wherein R 1 is selected from the group consisting of —H, —F, —Cl, —Br, and —I; R 2 is selected from the group consisting of —H, —F, —Cl, —Br, —I, —C 1-6 alkyl, —C 1-6 alkenyl, and —C 1-6 alkynyl; R 3 is selected from the group consisting of —H and —NO 2 ; and R 4 is selected from the group consisting of —H, —C 1-6 alkyl, —C 1-6 alkenyl, —C 1-6 alkynyl, —OC 1-6 alkyl, —OC 1-6 alkenyl, and —OC 1-6 alkynyl; and salts and esters thereof. |
| priorityDate | 2007-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 542.