| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_828b779fb17f940f59dbed256f4be6b6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5256
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16132
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16243
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 |
| filingDate |
2008-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cef14fdfe404de76a0db2ed5e4da5aef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95f4e096b8e85e347450c62eedfcf526
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae9ab906a11b718617a39f1efdf9e2e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ef6ba5efb155c5440bf0965f614e3f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64e2b161af8d8909a7b750063126e2f0 |
| publicationDate |
2010-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010136052-A1 |
| titleOfInvention |
Replication deficient influenza virus for the expression of heterologous sequences |
| abstract |
The present invention covers a novel replication deficient influenza virus comprising a modified NS1 segment coding for a NS1 protein lacking a functional RNA binding domain and functional effector domain and a heterologous sequence inserted between the splice donor site and the splice acceptor site of the NS gene segment. Further the use of the virus as vector for expression of various proteins like chemokines, cytokines or antigenic structures is covered, methods for producing virus particles using said virus vector as well as its use for production of vaccines. Also a fusion peptide comprising part of the N-terminus of an NS1 protein and a signal sequence fused to the C-terminus of said NS1 peptide is covered. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I681191-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11442069-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10392604-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010322970-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013183740-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10480013-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9771564-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10125374-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8592196-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014510517-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012164175-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2676139-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2676139-A4 |
| priorityDate |
2007-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |