| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_201e5a1185d0ecf0ee81cda71f8a0cb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4370d8ab764d5a4b7bb5e1e67c227339
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ffce062dbc5418db8dae5daa1b78590
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4c1f7e8cc4cbc0e56831f3b11b8d6f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d01c5bf123b5cc9c0dabc18eb036caf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45cc3ab603d4e40b73340ce9d16c4c36 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-0693 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-774
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-553 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 |
| filingDate |
2009-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc580688aab2ca61267e457c278be82a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1873231353a768918221d913014b506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aba98d1f6252e16cf6bc468b02f8172
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_020710bb95dc2ecebc649ca4d1c771f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca45fe8cee551bee6177eccdb851f59a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_360e3b0a9e13884cee79f1fbb740f126 |
| publicationDate |
2010-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010129856-A1 |
| titleOfInvention |
Methods and Devices for Cell Signaling Under Pulse Stimulation |
| abstract |
The disclosure provides a device for measuring cellular responses under controlled environments. The disclosure also provides an array of devices for measuring cellular responses under controlled environments. The disclosure also provides methods to study cell signaling using the devices. By using microfluidics, the disclosure enables study of cell signaling under well-defined environment conditions. Such capability can be used for differentiating long-acting ligands from short-acting ligands, for determining the kinetics of receptor resensitization and functional recovery of receptor signaling, and for differentiating the sensitivity of a cell type to laminar flow-induced stress force. Through combination with conventional static label-free cell assays, the full spectrum of a drug compound can be studied in details, thus creating a complete representation of its pharmacology acting on living cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9696275-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9488637-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017117243-A1 |
| priorityDate |
2008-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |