Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bc5292a07e34d16eb1d033a16d3aec3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6888 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate |
2007-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bf4a61a9721c677eb302394819b4ca5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_410cf65255d5597028f6b11ab9a1a4c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bb06804c2ecdf113c0fa36f0d35ffd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_640a15f0e5e7c012d98cad5e46555f30 |
publicationDate |
2010-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010129358-A1 |
titleOfInvention |
Method of detecting ocular diseases and pathologic conditions and treatment of same |
abstract |
Ocular diseases affecting the macula or the vasculature of the eye affect a wide variety of individuals. In particular, Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss in the developed world and has a significant genetic predisposition. Methods of analyzing one or more mutations in the HtrA1 gene in order to identify individuals with a presusceptability to development of an ocular disease and a pathologic condition of the eye and diagnose those currently suffering from an ocular disease or a pathologic condition of the eye are provided. The methods of the present invention may further include analysis of the CFH gene in order to identify individuals with a presusceptability to development of an ocular disease and a pathologic condition of the eye and diagnose those currently suffering from an ocular disease or a pathologic condition of the eye. Compositions and methods for treating ocular disease and pathologic conditions of the eye are also provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8232056-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102106807-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9738727-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200040343-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010166743-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10421821-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10421822-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11512143-B2 |
priorityDate |
2006-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |