| abstract |
Disclosed is a compound which is useful as an 11β-hydroxysteroid dehydrogenase type 1 inhibitor. n A compound represented by the formula: n n n n n n n n n n its pharmaceutically acceptable salt, or a solvate thereof, n wherein R 1 is optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted heterocycle or optionally substituted heterocyclealkyl, n X is —O—, —NR 3 —, —NR 3 C(═O)— or —NR 3 S(═O) 2 —, n R 2 is optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl or optionally substituted heteroarylalkyl, n R 3 is hydrogen or optionally substituted alkyl. |