http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010112594-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_853ea113c1f9471f1d90446a5b1acb0b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-1475 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2010-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9efd7cd6914f920d283a87bb054b8e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b9c7f2062444348b5f0583ce17ab909 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48ca03673f929e4323a9fec76b763529 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d44680965fa8e6acc5da31960d5a0de |
| publicationDate | 2010-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2010112594-A1 |
| titleOfInvention | Method for enumerating mammalian cell micronuclei with an emphasis on differentially staining micronuclei and the chromatin of dead and dying cells |
| abstract | The present invention relates a method for the enumeration of mammalian cell micronuclei, while distinguishing micronuclei from the chromatin of dead and dying cells. The method utilizes differential staining of chromatin from dead and dying cells, to distinguish the chromatin from micronuclei and nuclei that can be detected based upon fluorescent emission and light scatter following exposure to an excitatory light source. Counting of micronuclei events relative to the number of nuclei can be used to assess the DNA-damaging potential of a chemical agent, the DNA-damaging potential of a physical agent, the effects of an agent which can modify endogenously-induced DNA damage, and the effects of an agent which can modify exogenously-induced DNA damage. Kits for practicing the invention are also disclosed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014164312-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9857358-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9470694-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11016101-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10802013-B2 |
| priorityDate | 2004-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 171.