Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2b5f23ffe49931efdd1e0408b53f956 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cba02b1c3c29b77833574b4ee9c73d87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_107bb033450778bd007ba3f38f86b085 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 |
filingDate |
2007-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcc0c6221830e98bbc0d25fdf86557b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc2b5c56d5b66ad94e6df2d8850dcaf7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5446ba855c6d67c54e9a2019973f39bc |
publicationDate |
2010-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010111955-A1 |
titleOfInvention |
Hedgehog signaling pathway proteins and uses thereof |
abstract |
The present invention discloses a component in the hedgehog signaling pathway that can be useful in the treatment and diagnosis of hedgehog signaling pathway associated disorders. In this regard, the present invention discloses that RanBPM regulated the stability of hedgehog signaling molecule, smoothened (SMO) and that inactivation of RanBPM by siRNA prevented growth and metastasis of cancer cells. |
priorityDate |
2006-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |