| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45ebf9a6c25811ff297c85169e2933fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42717d81c91230167722871953a5b0f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_290ca2ca19a114f0ee7dcafac21e383a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4605e9d24d012d940673e1afdc11161e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 |
| filingDate |
2007-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4602dd7f54e17bf60602c9f9e5684754
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d1f236c66b67d55e60993a61994ed37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ede9158b2daaf77213fd2f3d27e98dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4403bc8fb61e592185ea701bdea75941 |
| publicationDate |
2010-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010092564-A1 |
| titleOfInvention |
Composition of and Method for Preparing Orally Disintegrating Tablets |
| abstract |
An improved orally dissolving tablet (ODT) and method of manufacture is provided. The improved ODT disclosed herein are prepared by direct compression of a mixture of pharmaceutical excipients including at least one water-insoluble hydrophobic inorganic salt in combination with at least one water-insoluble inorganic salt with less hydrophobicity compared to the water-insoluble hydrophobic inorganic salt component. These components may be formed into granules, and may include other commonly used excipients. In an illustrative embodiment, the granules are formed into tablets by direct compression, optionally using a lubricant. The fast disintegrating tablets prepared using these components exhibit desirable performance properties such as sufficient hardness, low friability, quick disintegration time and good mouth-feel when compared to conventional ODT. A further advantage is that the improved ODT may be manufactured using commonly available manufacturing equipment for granulation, blending and tableting. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10864165-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017047586-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3345626-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010278901-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010222427-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8840924-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010316585-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9012499-B2 |
| priorityDate |
2006-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |