Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a551cabbb1cdd0bbfe4b0bf1908781d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7bcad635f08ae5ef4159a2b96ddc6877 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c50a38897767b90b3f9e84925e7f9b69 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3633 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3641 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-148 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-129 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-48 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-00 |
filingDate |
2008-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fa4125e0bc074592304b25e53fcc173 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7613d3572028b71d7534d47e010d5fbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3223afef5dcefbacb267293aa09531c |
publicationDate |
2010-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010087839-A1 |
titleOfInvention |
Mesh comprising ecm |
abstract |
The present application discloses that incorporation of dermatan sulfate and/or HA in composite scaffolds of certain polymers gives rise to a chondrogenic effect on chondrocytes resulting in formation of cartilage that resembles the natural ECM. This effect with dermatan sulfate as the primary additive has not previously been seen. The composites are formed by incorporation of dermatan sulfate finely dispersed particles optionally nanoparticles or as molecular dissolutions in a polymer matrix with no bonding between the DS and the matrix, providing the DS to the chondrocytes in an accessible non-crosslinked form. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015006436-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016213815-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9271821-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10327884-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012082581-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012082581-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013126718-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013190893-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9308069-B2 |
priorityDate |
2007-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |