abstract |
There are disclosed compound of Formula (I) or (II) wherein A 1 , A 2 , A 3 , A 4 and A 5 , which may be the same or different, represent N or CR 1 , R 9 represents -L-R 3 , in which L is a single bond or a linker group and R 3 represents hydrogen or a substituent and in addition, when an adjacent pair of A 1 -A 4 each represent CR 1 , then the adjacent carbon atoms, together with their substituents may form a ring B, when A 5 represents CR 1 , then A 5 and N—R 9 , together with their substituents may form a ring C, or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the therapeutic and/or prophylactic treatment of Duchenne muscular dystrophy, Becker muscular dystrophy or cachexia. |