| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85ca1fab0e79201b8313b32b53286259
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2c8c1e6bd8e99a3e754ac236b99d3b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1491949e4403ebb42099825be892891
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ca4bf611bd1d25db7553bfff299e68a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47050998d60cafca999ec816f0308e26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_950440045b85147ca0003dd5976c6ad7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-216
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate |
2007-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f98a75d1bf8433e5d3a571653fd5a20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e16a483501f54fdab4951ade71a2ab6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dc011224779538bc657ec17809c02cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37645f259525d3d5e2e82a281d53fd0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4fbe22c153f8eeb179a7fd4659f0269
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a453acacfdaac3fe346c3741d17ab40c |
| publicationDate |
2010-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010048650-A1 |
| titleOfInvention |
Two pore channels as a therapeutic target to protect against myocardial ischemia and as an adjuvant in cardiac surgery |
| abstract |
The present invention relates to methods and compositions for modulating the activity of two-pore domain K+ channels (“K2P channels”) as a means for inducing preconditioning protection. Such preconditioning can be used to reduce the effect of ischemia associated with ischemic heart disease, myocardial infarcation or cardiac surgery. The invention is based on the discovery that the myoprotective current induced by short periods of ischemia is carried by a non-classical two-pore domain K+ channel. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011056572-A1 |
| priorityDate |
2006-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |