Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0bf0928b608797b70bbc2b91c7e52e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-747 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23G3-366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23G4-123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-99 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-747 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23G3-366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23G4-123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-99 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-99 |
filingDate |
2007-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccbf54008d4891bafb1d7ed4c18e728b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b35921b4a27484993e25c40b4b740091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6b137c0aae200f70a90e38e108f0dbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f25ad9471e0a8491ecffb8e6809594aa |
publicationDate |
2010-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010047190-A1 |
titleOfInvention |
Uses and methods for preventing and/or treating caries caused by mutants streptococci |
abstract |
The present invention relates to the use of a microorganism belonging to the group of lactic acid bacteria or a mutant or derivative thereof, characterized in that it is capable of specifically binding to a bacterium belonging to the group of mutans Streptococci, wherein the specific binding is (i) resistant to heat treatment; and/or (ii) resistant to protease treatment; and/or (iii) calcium-dependent; and/or (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva, for the preparation of an anticariogenic composition for the treatment or prevention of caries caused by mutans Streptococci other than Streptococcus mutans . Preferably, the specific binding can be assayed as follows: (a) growing said microorganism to stationary phase; (b) mixing said microorganism with a bacterium belonging to the group of mutans Streptococci which has been grown to stationary phase; (c) incubating the mixture obtained in step (b) under conditions allowing the formation of aggregates of said microorganism and a bacterium of the group of mutans Streptococci; and (d) detecting aggregates by the occurrence of a pellet. Another aspect of the present invention is a method of prophylaxis or treatment of caries caused by mutans Streptococci other than Streptococcus mutans , comprising administering a microorganism belonging to the group of lactic acid bacteria characterized in that said microorganism is capable of specifically binding to a bacterium belonging to the group of mutans Streptococci or a mutant, derivative, analog or fragment of said microorganism. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11147845-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012019058-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8853382-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3424516-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2667883-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8591882-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022192453-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102250603-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016193302-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10835485-B2 |
priorityDate |
2006-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |