| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c50a38897767b90b3f9e84925e7f9b69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38cd9ae8ed88827622d4b8cd2e77caee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3cbd9eb240385f433ae8a368189eed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4471cb5e5f3841893dcd446776544111 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate |
2008-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_179f40772ae13f670fd69d4089e56afa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f6f9214de4ee24904672fd47b254e83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cc27321b0b14e6f125983970219c005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b056295b8d3879ae59de65d5528c2d6 |
| publicationDate |
2010-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010034868-A1 |
| titleOfInvention |
Scaffolds for the regeneration of cartilage |
| abstract |
The present application discloses that incorporation of dermatan sulfate and/or HA in composite scaffolds of certain polymers gives rise to a chondrogenic effect on chondrocytes resulting in formation of cartilage that resembles the natural ECM. This effect with dermatan sulfate as the primary additive has not previously been seen. The composites are formed by incorporation of dermatan sulfate finely dispersed particles optionally nanoparticles or as molecular dissolutions in a polymer matrix with no bonding between the DS and the matrix, providing the DS to the chondrocytes in an accessible non-crosslinked form. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010049938-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8504594-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013204392-A1 |
| priorityDate |
2007-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |