| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69108fc12b940ede105638f37f06080b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2991 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0017
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0065
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-587
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0093 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B32B5-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B05D7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-77 |
| filingDate |
2009-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20c53aef8fec0bd8384078b220a91b68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f708b9ea52a6c10b2e5af7f5eea758e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01340b0a918f7139615390d07e0b9b73 |
| publicationDate |
2010-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2010034742-A1 |
| titleOfInvention |
Modular monolayer coatings for selective attachment of nanoparticles to biomolecules |
| abstract |
Nanoparticles are functionalized for use as bio-imaging probes using a novel, modular approach. Particle surface modification is based on a phosphonate monolayer platform on which was built a multi-segmented, multi-functional film: the first segment provided hydrolytic stability, the second aqueous suspendability, and the third, selectivity for cell attachment. In vitro imaging experiments visualized nanoparticle—cell surface binding. Peptide-derivatized nano-particles were not displaced from cells by soluble peptide. Methods for coating the host particles and use of rare earth ion-doped particles in imaging methods and photodynamic therapy methods are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10232365-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011171735-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8337692-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010320092-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8927299-B2 |
| priorityDate |
2008-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |