| abstract |
Compounds having the formula (I), n n n n n n n n n n and pharmaceutically acceptable salts, and solvates thereof, are useful as kinase inhibitors, wherein:n two of X 1 , X 2 , and X 3 are N, and the remaining one of X 1 , X 2 , and X 3 is —CR 1 ; R 1 is hydrogen or —CN; and N, G, Z, R 2 , R 3 , R 4 , R 5 , and R 6 are described in the specification. nn Also disclosed are pharmaceutical compositions containing compounds of formula (I), and methods of treating conditions associated with the activity of p38 kinase and/or conditions associated with the activity of LIM kinase. |