abstract |
The invention concerns pyrimidine derivatives of Formula (I) wherein each of p, R 1 , R 2, q, R 3 , r, R 4 , s, t, X 1 and Q 1 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in a method for producing an anti-proliferative effect in a warm blooded animal such as man. |