Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ccf144959040566bfd6c8a6e85116f39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f48e12c4d1ccad215ddafa32eaa50a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_948c919d4e2f7f8d59931d9961ee2083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fa174c12a6882c306d43ce3099498d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34f6c95c09224ce2a47dddddd49f2878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_085b5672abc04bf62712115ab44250c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5ec89a17f3de953b6b0f8b5b461198c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a083cb7149c413a7398f45cb4fad561 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
filingDate |
2007-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b981462be59a2327b7b579a8b37f256 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf4432c5d710ff0984ceef908861c0d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24e19022b9f5d7cd839fa6649077ebda http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1f476fc75e4068eb91929183cd32082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c0cf6b0a7af9e372f4f9d6251b49a2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d52b9f4275c24a6b2fed0d49681d2ec5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_319c6950880829cdb293e64e20133a8b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45c1ce89c5e2e8378399356303ab17e4 |
publicationDate |
2010-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010015243-A1 |
titleOfInvention |
Method for preparing materials having antithrombotic activity from muskrat musk and materials obtained from the method |
abstract |
Disclosed herein is a method of preparing an antithrombotic agent from muskrat musk and an antithrombotic agent having a high potency obtained therefrom, wherein the antithrombotic agent is prepared by treating muskrat musk with ethanol to obtain an ethanol extract; carrying out two normal phase column chromatographies while raising the combination ratio of hexane and ethyl acetate to obtain numerous fractions; carrying out thin layer chromatographies and identifying the material patterns of the fractions with UV lamps and 10% sulfuric acid to divide the materials which have a similar moving distance into groups; measuring a thrombin time of each group to isolate a group having a potent antithrombotic activity; carrying out a reverse phase column chromatography while raising the combination ratio of acetonitrile and water to obtain numerous fractions; and isolating an antithrombotic agent material having a high potency therefrom. According to the present invention which provides an antithrombotic agent having a high potency from muskrat musk, the value added of muskrat musk is raised. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015238539-A1 |
priorityDate |
2006-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |