Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c72d118f5664072de841f9c5c34b9d99 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 |
filingDate |
2008-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd2d8cdf420e97687aa5e282ddaa9b9c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_748540162a3e7edd75199ea3d714e433 |
publicationDate |
2010-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2010009411-A1 |
titleOfInvention |
Method and Kits for Repairing Nucleic Acid Sequences |
abstract |
Methods and kits for DNA repair are provided. The methods and kits described herein repair multiple types of DNA damage. The kit may include a plurality of enzymes to repair a greater variety of lesions than any single enzyme is capable of repairing. Repair of damaged DNA may include releasing damaged bases from the DNA strand, nicking the DNA at the damaged sites, translating the nicks via 5′-3′ exonuclease activity, and sealing the nicks. The enzymes employed in the repair process may then be heat-inactivated, thereby obviating a purification process. The repaired DNA may then be analyzed using a variety of DNA analysis methods. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11713484-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105848693-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11542535-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014343265-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020325533-A1 |
priorityDate |
2008-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |