Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 |
filingDate |
2009-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc84e35e696eb20e46a3485e087705e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55afeef7f1943ef421639416eaaa5fd1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c432d4a3aed9e65661f00879434b91a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b88683040bb00f03a2f374724075733 |
publicationDate |
2009-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009318533-A1 |
titleOfInvention |
Annexin A9 (ANXA9) Biomarker and Therapeutic Target in Epithelial Cancer |
abstract |
Amplification of the ANXA9 gene in human chromosomal region 1q21 in epithelial cancers indicates a likelihood of both in vivo drug resistance and metastasis, and serves as a biomarker indicating these aspects of the disease. ANXA9 can also serve as a therapeutic target. Interfering RNAs (iRNAs) (such as siRNA and miRNA) and shRNA adapted to inhibit ANXA9 expression, when formulated in a therapeutic composition, and delivered to cells of the tumor, function to treat the epithelial cancer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9828643-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012159030-A1 |
priorityDate |
2008-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |