| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99f7850dd23ac24ee02136cbb96b10fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_847d6b9e1064361541f1aba4f73616b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_deb15001b4dbc8c76822b4c9f3a51c24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a03cc0d3f2faf6a29ef48a9b5c13f051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aed89094b08c7012f61f6fac1dc02da2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a3f1cbd4472dbb6a4ca154ad4ac2334
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c13127574f593cc78370cfe1e04d2d0f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-10 |
| filingDate |
2005-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e586d953b5764bde52983ad67261111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_213b20b7cd16e000fbcee1a5c5bf835a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bd4de129c80b25168ab57994ee19300
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c192c363214bc9a4853ab56ae35ac0e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cac88b101de6d0ef354e133e5b5323e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43ae0ef2ed77a2db18acc2c87a012ba2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0700f374a9e270f418d45158054b6e1d |
| publicationDate |
2009-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2009286990-A1 |
| titleOfInvention |
Process for preparing irbesartan |
| abstract |
A process for preparing irbesartan comprises pentanoylation of cycloleucine in the presence of sodium hydroxide to form n-pentanoyl cycloleucine, condensing this product with 2-(4-aminomethyl phenyl) benzonitrile using dicyclohexyl carbodiimide and 1-hydroxy benzotriazole as a catalyst to form the 4-(&quest-N-pentanoyl amino) cyclopentamido methyl-2′-cyano biphenyl compound, and then cyclizing using trifluoroacetic acid in the presence of an aromatic solvent to form cyano irbesartan. Cyano irbesartan is converted to irbesartan by reaction with tributyltin chloride and sodium azide in the presence of an aromatic solvent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8106216-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010056797-A1 |
| priorityDate |
2004-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |