http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009275595-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cd3ea6c52ef8544c67c051a2ef489b3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 |
filingDate | 2005-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65a04604dda5f2862c74112a40f0ee41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b56bd8a849df2115ec5c7e7f4644272a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bb6f35d6df7cc72a9df3d95ab234022 |
publicationDate | 2009-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2009275595-A1 |
titleOfInvention | Method for reduction, stabilization and prevention of rupture of lipid rich plaque |
abstract | There is to provide is an agent for reduction of a lipid rich plaque, stabilization of a lipid rich plaque and/or prevention of rupture of a lipid rich plaque in an atherosclerotic lesion comprising an effective amount of 2-[4-[2-(benzimidazole-2-ylthio)ethyl]piperazin-1-yl]-N-[2,4-bis(methylthio)-6-methyl-3-pyridyl]acetamide (hereinafter, referred to as compound 1), its pharmaceutically acceptable salt or a hydrate thereof and Pitavastatin, and a pharmaceutically acceptable carrier, wherein the agent is intended to be simultaneously administered, or separately administered with interval of time to a patient in need thereof. There is also to provide a method for reduction of a lipid rich plaque, stabilization of a lipid rich plaque and/or prevention of rupture of a lipid rich plaque in an atherosclerotic lesion, comprising simultaneously administering, or separately administering with interval of time an effective amount of the compound 1, its pharmaceutically acceptable salt or a hydrate thereof and an effective amount of Pitavastatin to a patient in need thereof. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006264965-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7884106-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007004749-A1 |
priorityDate | 2004-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 132.