Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b5d728d4890268356fcc07e6e53840c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 |
filingDate |
2006-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f21645af4d58cee74af78f9b18e9d0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd86dbc316a5d92a353726a01c391b8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aabba7c3bb729162d2eb7d4dea3d1a38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dc438d118fa78928900c713579075bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b54a8b44132fdc282b02f1df5c643346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62458bb062c404c65f74410c23f157d7 |
publicationDate |
2009-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009269400-A1 |
titleOfInvention |
Nanoparticulate and Controlled Release Compositions Comprising a Cephalosporin |
abstract |
The present invention is directed to compositions comprising a nanoparticulate antibiotic having improved bioavailability. Preferably, the antibiotic comprises nanoparticulate cephalosporin particles with an effective average particle size of less than about 2000 nm and are useful in the treatment of bacterial infection. The invention also relates to a controlled release composition comprising a cephalosporin or a nanoparticulate cephalosporin that in operation delivers the drug in a pulsed or bimodal manner for the treatment of bacterial infection. The nanoparticulate cephalosporin particles may be formulated as a controlled release drug delivery system whereby the particles are coated one or more times with one or more natural or synthetic hydrophilic or hydrophobic polymer coating materials or dispersed throughout a natural or synthetic hydrophilic and/or hydrophobic polymer matrix. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101874784-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115487154-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016088041-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9012511-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011057266-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011146583-A2 |
priorityDate |
2005-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |